MMP13 antibody

Catalog No. ABIN7268419

This Rabbit Monoclonal antibody specifically detects MMP13 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for MMP13 antibody (ABIN7268419)

Target: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MMP13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MMP13 Antibody

Purpose: MMP13 Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human MMP13

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MMP13

Target: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Alternative Name: MMP13

Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016],CLG3, MANDP1, MDST, MMP-13,Angiogenesis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Extracellular Matrix_MMPs,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Invasion and Metastasis,Signal Transduction,Tumor biomarkers,Ubiquitin,MMP13

Molecular Weight: 54kDa

Gene ID: 4322

UniProt: P45452